Current research on sepsis-related gene polymorphisms mainly involve TNF family members, IL family members, heat shock protein 70 (HSP70) (Giacconi et al., 2014), CD14, plasminogen activator inhibitor (PAI-1), and mannose-binding lectin (MBL) (Özkan et al., 2012; Mao et al., 2017). This evidence concerns the gene TNF and Sepsis.