The TRP family member TRPM4 has received much attention due to its implication in many physiological functions such as cardiac activity (Guinamard and Bois, 2007; Liu et al., 2010; Stallmeyer et al., 2012; Guinamard et al., 2015; Piao et al., 2015), immune response (Launay et al., 2004; Barbet et al., 2008; Hemmer et al., 2015), cancer (Sagredo et al., 2018), arterial constriction (Earley et al., 2004), insulin secretion (Cheng et al., 2007), and cell death (Simard et al., 2012). Here, TRPM4 is linked to cancer.