GLP1R and Sepsis: In a rat model of acute kidney injury in early sepsis, Glp-1 receptor expression in renal tubules increased, and the induction of Glp-1 receptor expression prevented inflammation and sepsis-induced AKI (Choi et al., 2019), a Glp-1 analog, by blocking sodium hydrogen exchanger, enhancing renal tubular sodium (Girardi et al., 2008), and reducing the activity of angiotensin (Jeppe et al., 2013); thus, playing a role in kidney protection.