Kaplan-Meier analysis indicated that the elevated expressions of PI3K (p = 0.0025) (Supplementary Figure 1H) and AKT (p = 0.0025) (Supplementary Figure 1I) are significantly associated with reduced overall survival in liver cancer patients, while mTOR levels had no significant association with survival (Supplementary Figure 1J). Here, AKT1 is linked to liver cancer.