NFKB1 and inflammatory bowel disease: It is reported that miRNAs participate in autophagy by regulating the responses of unfolded proteins to the autophagy and IBD-related endoplasmic reticulum (ER) stress, which is achieved via the modulation of the mTOR and NF-κB signal pathways, which allows them to influence pro-/anti-inflammatory effects and inflammatory factors (Sohn et al., 2012; Krissansen et al., 2015; Boros and Nagy, 2019; Arab et al., 2021).