The most recent research into NGF treatments has focused on neurotrophic keratitis, dry eye disease, optic neuropathy and optic pathway glioma (Eftimiadi et al., 2021), and the treatment of corneal ulcers of different etiologies, treated by topical NGF application in more than 200 patients, is of major interest (Lambiase et al., 2012). The gene discussed is NGF; the disease is Optic neuropathy.