COL4A3 and chronic kidney disease: To assess the contribution of LCN2 to CKD progression and CKD-associated outcomes, we deleted Lcn2 from WT and Col4a3KO mice and studied the phenotype of WT, Lcn2KO, Col4a3KO, and mice with compound deletion of Lcn2 and Col4a3 (CPD: Lcn2KO/Col4a3KO) littermates.