The protein levels of hnRNPL, but not its mRNA levels (Supplementary Fig. 2C, D), were significantly increased in FBXO16 silenced or depleted ovarian cancer cells (Fig. 5G, H), suggesting the regulation of hnRNPL by FBXO16 occurs at the post-transcriptional level. Here, FBXO16 is linked to ovarian carcinoma.