The main similarities included overexpression of STAT1 and underexpression of RARA. However, only NELF can be found within 241 loci that were examined in IBD patients by genome-wide association studies (de Lange et al. [18]), notably in an region of dense immune gene clustering on chromosome 6 that also contains HLA and TNF genes (top SNP rs6927022). This evidence concerns the gene TNF and inflammatory bowel disease.