IL13 and asthma: A hallmark of the predominant asthma subtype is the stimulation of the adaptive immune system [2], specifically a Th2-type response, with involvement of interleukin (IL)-4 and IL-13, as well as antigen-specific immunoglobulin (Ig) type E. Type 2 innate immunity typically involves type 2 innate lymphoid cells, especially in older patients.