STYK1 and cancer: For the analysis of cellular functions of lnc-STYK1-2 during cancer development, we then knocked down the expression of lnc-STYK1-2 in T24 and 5637 cells by transfection with siRNA targeting lnc-STYK1-2; then, the results of qRT-PCR showed that the expression of lnc-STYK1-2 was successfully silenced (Fig. 2B).