The network results displayed 12 modulators function as risk factors in PAAD patients, including LRPPRC, IGF2BP2, IGF2BP3, HNRNPC, FMR1, EIF3H, EIF3A, FTO, CBLL1, RBM15, YTHDF3, and KIAA1429. Here, IGF2BP3 is linked to pancreatic adenocarcinoma.