Expression of 28 m6A RNA methylation modulators was extracted from 167 healthy samples from GTEx database and 140 patients with PAAD integrated from TCGA database (Fig. 1A), All the m6A RNA methylation modulators showed a high expression in pancreatic carcinoma than normal pancreatic tissue except METTL3. Here, METTL3 is linked to exocrine pancreatic carcinoma.