The most commonly mutated genes were TP53 (50.7%), TERT (38.7%), and CTNNB1 (25.3%) in non‐sarcomatoid HCC and TP53 (73.3%), TERT (53.3%), and CDKN2A (26.6%) in sarcomatoid HCC (Figure 3C). The gene discussed is CDKN2A; the disease is hepatocellular carcinoma.