In addition, the ANGPTL4 expression in GBC stromal cells was significantly associated with tumor differentiation (p < 0.01), liver metastasis (p < 0.05), venous invasion (p < 0.01), and Nevin staging (p < 0.05), while it was not correlated with patient's sex, age, tumor location, tumor size, histological type, lymph node metastasis, and curability (all p > 0.05; Table 1). The gene discussed is ANGPTL4; the disease is neoplasm.