DICER1 and global developmental delay - lung cysts - overgrowth - Wilms tumor syndrome: The discussion of whether GLOW syndrome is a separate entity is ongoing: meanwhile some patients with pathogenic germline variants in DICER1 are reported matching the phenotype of GLOW syndrome and not all mosaic variants in the RNAase IIIb domain lead to the typical GLOW syndrome phenotype but instead are in line with the variable expressivity and reduced penetrance of DICER1-associated features [3].