The tumor vessel diameter increased significantly (p < 0.01) in [Hyd(+)] compared to [Hyd(−)]—mean vessel diameter (MVD) in [Hyd(+)] = 51.7 ± 4.5 μm; [Hyd(−)] = 32.4 ± 1.3 μm; sham-treated = 9.5 ± 0.6 μm (Fig. 6D). The gene discussed is UBR5; the disease is neoplasm.