Specifically, analyses of total and poly-ribosomal RNA revealed a substantial enrichment of DUSP6 mRNA specifically in the poly-ribosomal fraction of eIF2αA/A compared to eIF2αS/S tumor cells after normalization to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and ACTIN mRNAs in the corresponding total and poly-ribosomal mRNA fractions (Fig. 3c). Here, DUSP6 is linked to neoplasm.