As expected from the preceding data, IWS1 expression, U2AF2 exon 2 inclusion, and FGFR2 exon 8 skipping are indicators of poor prognosis in TCGA patients with lung adenocarcinomas, harboring EGFR, but not KRAS mutations (Fig. 8h). The gene discussed is U2AF2; the disease is lung adenocarcinoma.