Furthermore, the significant enrichment of DEGs in canonical pathway as well as diseases and functions were investigated based on IPA, suggesting that ‘colorectal cancer metastasis signaling, Wnt/β-catenin signaling, Wnt/ca+ pathway’ (Fig. S2A) and cell proliferation, death and other functions (Fig. S2B) would be affected by DEPDC1B. This evidence concerns the gene DEPDC1B and colorectal cancer.