The pB-ALL comprises 90% of B-ALL cases and is characterised by the morphologic type (French–American–British (FAB) classification systems) of ALL-L1 or ALL-L2; Flow cytometric analysis with combination of CD19, CyCD22, CyCD79a, TdT, HLA-DR and/or CD22, CD10, CD20, CyIgM, CD34 appear in pB-ALL [2–4]. This evidence concerns the gene DNTT and acute lymphoblastic leukemia.