Afterward, GeneGo Metacore annotations of each biological process suggested that genes coexpressed with PSMC1 were involved inG-protein-coupled receptor (GPCR)- and apoptosis-related pathways and networks such as “Chemotaxis_Lysophosphatidic acid signaling via GPCRs”, “Development_Positive regulation of WNT/Beta-catenin signaling in the cytoplasm”, and “Apoptosis and survival_Regulation of apoptosis by mitochondrial proteins”, and play essential roles in breast cancer (Supplementary Figure 6 and Supplementary Table 3). The gene discussed is CTNNB1; the disease is breast carcinoma.