CXCR3 and familial pancreatic carcinoma: However, it needs to be noted that in pancreatic cancer expression of both CXCL10 and CXCR3 in tumor tissue have been correlated with metastasis and poor prognosis (Cannon et al., 2020; Hirth et al., 2020; Liu et al., 2011; Lunardi et al., 2014; Romero et al., 2020).