CP and cancer: Taking CP resistance as a specific example of a drug facing the challenges of chemoresistance, several global studies investigating changes in the transcriptome or the proteome found an association between CP resistance and aberrant levels and possibly activity of ribonucleoprotein complexes and ribosomes (e.g. [18]), Furthermore, certain RBPs that modulate the sensitivity of cancer cells to CP and other cytostatic drugs inhibiting cell division have been identified, albeit without knowing the underlying targets and functions.