Figure 2A and Figure S1A). Among them, 11 genes (CASP1, PYCARD, APIP, FOXO3, IL18, GSDMA, GSDMC, CASP4, GSDMB, NLRP1, and NAIP) were downregulated while 9 genes (NLRP9, DHX9, CASP3, NLRC4, AIM2, NLRP3, IL1B, GSDME, and GSDMD) were upregulated in tumor tissues. In addition, 13 genes showed significant associations with OS (Figure 2B). The gene discussed is GSDME; the disease is neoplasm.