Figure 2A and Figure S1A). Among them, 11 genes (CASP1, PYCARD, APIP, FOXO3, IL18, GSDMA, GSDMC, CASP4, GSDMB, NLRP1, and NAIP) were downregulated while 9 genes (NLRP9, DHX9, CASP3, NLRC4, AIM2, NLRP3, IL1B, GSDME, and GSDMD) were upregulated in tumor tissues. In addition, 13 genes showed significant associations with OS (Figure 2B). This evidence concerns the gene NLRP3 and neoplasm.