An elevated NT-proBNP level, which is accepted as a usual marker for HF diagnosis, may be linked with poor outcomes in acute respiratory dysfunction syndrome (ARDS) subjects.12 Moreover, a recent retrospective study suggested a possible direct cardiac injury in COVID-19 patients linking elevated levels of NT-proBNP levels to mortality.13 Therefore, this biomarker can also be utilized as a useful indicator for the severity of COVID-19 infection. The gene discussed is NPPB; the disease is hydrops fetalis.