FYN and acute kidney injury: However, there are several unanswered questions such as the following: (a) the delayed treatment of CORM2 on AKI was not studied, (b) the detailed mechanisms involved in the inhibition of H2O2-mediated Fyn-ER stress signaling by CORM2 have not been explored, and (c) protocol of optimal delivery and dosing and the possible treatment of CO in human diseases have not been recognized yet.