TIMP1 and infarction: Further analysis showed that EPC-Exos containing miR-218-5p and miR-363-3p mimic effectively suppressed infarction-induced myocardial damage by inhibiting inflammation and macrophage infiltration, downregulating collagen expression, and increasing capillary density, as shown by histochemical staining and analysis of collagen-1, collagen-3, and Timp-1-4 expression.