RBM8A and metastatic malignant neoplasm in the lymph nodes: In addition to liver cancer, studies have also reported that the expression level of RBM8A in gastric cancer and colon adenocarcinoma is higher than that in adjacent tissues, and its expression level is positively correlated with tumor size, depth of invasion, and lymph node metastasis; RBM8A can also be used as an independent prognostic factor that affects the overall survival rate of patients [27, 28].