Additionally, the Hamartomatous polyposis syndromes that englobe the syndrome of PeutzJeghers (PJS), the syndrome of Juvenile Polyposis (JPS), and the syndrome of Cowden are autosomal dominant syndromes caused by germline mutations in STK11/LKB1, BMPR1A/SMAD4, and PTEN, respectively [18]. Here, STK11 is linked to Cowden disease.