In different animal models, EPC transplantation indeed increased survival rate and improved liver fibrosis via suppressing HSCs, reducing serum levels of aspartate aminotransferase (AST) and ALT, and increasing hepatocyte proliferation and expression of hepatocyte growth factor (HGF) and vascular endothelial growth factor (VEGF) [91–95]. The gene discussed is VEGFA; the disease is Hepatic fibrosis.