37% (10/27) of the pathogenic CNVs identified were in three (BRCA1, BRCA2, and PALB2) of the six high penetrance breast and/or ovarian cancer genes (BRCA1, BRCA2, PALB2, TP53, PTEN, and CDH1) identified by the NCCN (see text footnote 2). The gene discussed is PALB2; the disease is ovarian carcinoma.