As a comparison in a recent study with an extended targeted panel, including 64 hereditary cancer predisposition genes, PV detection rate of 19.2% was reported in 496 patients with hereditary breast and ovarian cancer and 12% patients were positive for a PV in BRCA1 and BRCA2 genes (Shin et al., 2020). Here, BRCA2 is linked to ovarian carcinoma.