Instead, the increased expression of Slc7a8/Lat2 at early stage of macrophage infection from our analysis, the high affinity of LAT2 for glutamine (50), and the critical role of LAT2 in glutamine-dependent mTOR activation for the metabolic programming of cancer cells (71), suggest that LAT2 could be a main player in glutamine uptake by Mtb induced M1-like macrophages. The gene discussed is LAT2; the disease is infection.