The results showed that the conventional anti-MSLN CAR-T cells could significantly inhibit tumor growth compared with the Mock-T cells in these mice; However, the anti-MSLN-sP CAR-T cells showed a significantly stronger capacity to regress tumors, as depicted by combined tumor growth curves and tumor weight measurements (Figures 4B, C), as well as individual tumor growth curves (Figure 4D). This evidence concerns the gene MSLN and neoplasm.