Mitoxantrone is similar to an embedding agent in the treatment of MS when it is embedded in DNA base molecules, which inhibits DNA synthesis and the presentation of antigens, such as T and B cells, reduces the secretion of inflammatory cytokines, such as tumor necrosis factor (TNF), and plays an immunosuppressive and neuroprotective role (Jeffery and Herndon, 2004; Martinelli et al., 2009). This evidence concerns the gene TNF and myeloid sarcoma.