Renal function was also analyzed according to the presence or absence of CKD, as measured by eGFR (MDRD) < 60 (n = 19) or ≥60 ml/min/1.73 m2 (n = 65) at the start of mTOR inhibitors; a significant improvement in renal function was noted in the CKD group after 12 months (Figures 4A,B). This evidence concerns the gene MTOR and chronic kidney disease.