Even Fusobacterium nucleatum (F. nucleatum), a bacterium that can cause colorectal cancer to be resistant to oxaliplatin and 5-fluorouracil by affecting the TLR4/MyD88 pathway, has been found to be more abundant in the cancer tissues of patients with pancreatic cancer than in nonpatient controls 155. Here, MYD88 is linked to familial pancreatic carcinoma.