Furthermore, the results showed that high PD-1 (PDCD1) mRNA level patients had poor prognosis in acute myeloid leukemia, cutaneous melanoma and renal carcinoma (Figure 3; all P<0.05), but had no impact on pancreatic carcinoma, hepatocellular carcinoma, lung cancer and breast invasive carcinoma (all P>0.05). The gene discussed is PDCD1; the disease is hepatocellular carcinoma.