SOAT1 and posterior cortical atrophy: Inhibition of cholesteryl ester formation with avasimibe, an inhibitor of Sterol-O-Acyl transferase 1 (SOAT1, also known as Acyl-CoA-Cholesterol Acyl transferase 1, ACAT1) in a cell culture model of PCa has been shown to reduce cell viability and in vitro indicators of cell migration and invasiveness.