Color intensity analysis of TRPM7 (Fig. 7) as well as of TRPM6 (Fig. 8) in tissues showed noticeable brownish pigments in the intracellular space in tissues from the four chamber walls of non-ischemic heart (obtained from a victim of traffic accident and serving as control; Figs. 7a,8a) and of an IHD heart (Figs. 7b,8b). Here, TRPM6 is linked to myocardial ischemia.