The study found that high ITGB1- and COL1A2-expression patients with gastric cancer had significantly lower survival rates than those with low expression of ITGB1 and COL1A2, which indicates that ITGB1 and COL1A2 are closely related to the occurrence and development of gastric cancer and their malignant progression. The gene discussed is COL1A2; the disease is gastric cancer.