These include the associations with midgut-derived NET (CDKN1B)10,13, lung NET (FHIT)56–58, pNET (TP53, MEN1, ATRX, DAXX and SETD2)3–5,7,15 and NEC (TP53, KRAS, MYC, APC and RB1, and chromothripsis)17,18,59,60. This evidence concerns the gene DAXX and neuroendocrine carcinoma.