One aNET displayed signs of BRCA2-associated homologous recombination deficiency (HRD), as determined using the CHORD classifier which is mainly based on deletions with flanking microhomology and 1–100 kb structural duplications (Fig. 2j; Supplementary Fig. 3). The gene discussed is BRCA2; the disease is hypoparathyroidism-retardation-dysmorphism syndrome.