To experimentally dissect the role of WDR62 in prostate cancer, we performed clonogenic survival assays in five prostate cancer cell models and observed a significant decrease in the colony formation following knockdown of WDR62 in all five models demonstrating WDR62 is required for prostate cancer proliferation or survival irrespective of AR status (Fig. 3C). This evidence concerns the gene WDR62 and Familial prostate cancer.