AKT1 and neoplasm: Analysis of common regulated genes by TXX-1-10 and rimonabant showed that TXX-1-10 and rimonabant generally exerted inhibitory effects on diverse tumor-associated biological processes, such as DNA replication, focal adhesion, and cancer-related pathways including cGMP-PKG signaling pathway, PI3K-Akt signaling pathway, and HIF-1 signaling pathway (Fig. 5B).