Similarly, we observed p53-dependent up-regulation for Zmat3-as, ua-Bahcc1, lincRNA-Spag9, and lincRNA-Gadd45γ across all tumor types, whereas Ltc4s-as and Bfsp2-as showed p53-dependent activation in the senescence-prone LA and SA cell lines (Fig. 3). The gene discussed is SPAG9; the disease is neoplasm.