GRIN2A and epilepsy: First, given that GluN2A subunits contribute significantly to PV and SSt IN synaptic NMDARs, this heterogeneity emphasizes the need to further elucidate the role of these neurons in epileptic syndromes, as the GluN2A subunit may be a critical determinant of some forms of epilepsy (Marwick et al., 2019).