Alveolar capillary dysplasia with or without misalignment of the pulmonary veins (ACD/MPV) is a lethal congenital lung disorder associated with heterozygous genomic alterations in the Forkhead Box F1 (FOXF1) gene locus. This evidence concerns the gene FOXF1 and alveolar capillary dysplasia with misalignment of pulmonary veins.