Other conditions that may present a clinical picture similar to Raynaud syndrome or VWF due to impaired blood flow are Thoracic outlet syndrome, Hypothenar hammer syndrome (HHS), Thenar hammer syndrome (THS) and Buerger’s disease, which are all associated with a partial or total blood flow impairment to the digits [7, 8]. The gene discussed is VWF; the disease is Raynaud disease.