In DLD-1 (p53S241F), SW480(p53R273H,P309S), HCT116(p53WT), and HCT116 p53−/− tumor cells expressing the exogenous R175H p53 mutant, Noxa protein expression was found to be induced, though some variation across cell lines was observed (Figure 1G). Here, TP53 is linked to neoplasm.