The results showed that S100A7 had no effect on the cell cycle distribution of KYSE‐30 or KYSE‐150 cells (Figures 4B and S2B); however, S100A7 overexpression inhibited cisplatin‐induced apoptosis of ESCC cells (Figures 4C,D and S2C, S2D). The gene discussed is S100A7; the disease is esophageal squamous cell carcinoma.