S100A7 and esophageal squamous cell carcinoma: The inclusion of S100A7 as a diagnostic factor for ESCC increased the AUC from 0.764 (95% CI: 0.686‐0.842) for diagnosis based on SCC and crfra21‐1 to 0.863 (95% CI: 0.802‐0.925) for diagnosis based on S100A7, SCC, and crfra21‐1 (Figure 2C, D).