CEACAM5 and bone metastasis: Univariate Cox regression analysis indicated that race, primary site, histology, grade, tumor size, regional nodes examined, LNR, liver metastasis, lung metastasis, bone metastasis, brain metastasis, TNM stage, T stage, N stage, CEA, perineural invasion, and median household income were significantly associated with OS in the training cohort (Table 2).