This idea had important practical consequences since it lead to propose that Angiotensin receptor blockers (ARB) and ACE inhibitors (ACE-I) commonly used to treat hypertension may favour viral propagation since they upregulate the viral receptor ACE2 (Ferrario et al., 2005), and should be discontinued (Diaz, 2020; Fang et al., 2020). The gene discussed is ACE; the disease is hypertensive disorder.