Several papers proposed that the downregulation of ACE2 is a key factor for the severity of CoViD-19 and suggested that ACE-I and ARB that limit the effects of Ang1-8 may be beneficial for CoViD-19 patients (Annweiler et al., 2020; Ciaglia et al., 2020; Gurwitz, 2020; Offringa et al., 2020; Sun et al., 2020; Verdecchia et al., 2020). Here, ACE2 is linked to COVID-19.